About Me

Currently, I hold an Assistant Professor position in Department of Automation and Applied Informatics (UPT) and a Bioinformatician position at the Center of Genomic Medicine from Victor Babes University of Medicine and Pharmacy Timisoara.

Current positions: Assistant Professor, Bioinformatician.
Education: PhD Degree (2020), Master Degree in System Engineering (2013), Master Degree in Web Technologies (2013), Bachelor's Degree in Computer Science (2011).

Scientific Interests

Bioinformatics, Machine Learning, Genomics - Working on those computational methods that can answer my questions.

Research Projects

Member in ongoing projects:
(1) SARS-CoV-2 genome sequencing and phylogenetic analysis of circulating strains in Romania,
(2) ImmunoGenomes UMFVBT 2019/2020.

Member in ended projects:
(1) Nutrigen (POC 2014-2020, ID_P_37_684, SMIS 104852),
(2) STOP (Horizon 2020, contract 774548),
(3) Increasing the capability of genetic and genomic research addressing perinatal and child development (PN-III-P3-3.1-PM-RO-MD-2016-0112)

Member in non-research projects:
(1) Asigura-ti Viitorul prin Educatie si Antreprenoriat – AVEA (POCU 2014-2020)

Publications

The list can be found here.

Contact

email: cristian.zimbru@aut.upt.ro
room: B612B

Teaching

Databeses used in Bioinformatics [RO]

Updating... see you in fall 2020 (SARS-CoV-2 edition)

Software Tools used in Bioinformatics [RO]

Updating... see you in fall 2020 (SARS-CoV-2 edition)

Computer Arhitecture [RO]

Updating... see you in fall 2020

Publications

For an updated list of publications please check: Google Scholar, ResearchGate, ORCID or BrainMap.

Journals & Proceedings

2020

Adela Chirita-Emandi, Nicoleta Andreescu, Cristian G. Zimbru, Paul Tutac, Smaranda Arghirescu, Margit Serban, Maria Puiu, „Challenges in reporting pathogenic/potentially pathogenic variants in 94 cancer predisposing genes - in pediatric patients screened with NGS panels”, Scientific reports, vol. 10, no. 1, pp 223, 2020;
DOI - https://doi.org/10.1038/s41598-019-57080-9

2019

Cristian G. Zimbru, Adriana Albu, Nicoleta Andreescu, Adela ChiritaEmandi and Maria Puiu, „Determining Splicing Signal Variation in Humans by Analyzing the Regulatory Splicing Motifs”, 2019 E-Health and Bioengineering Conference (EHB), 2019;
DOI - https://doi.org/10.1109/EHB47216.2019.8969983

Adriana Albu, Mădălina Sofia PaŞCa, Cristian G. Zimbru, „Medical Predictions: Naive Bayes Classifier vs Artificial Neural Networks” 2019 IEEE 13th International Symposium on Applied Computational Intelligence and Informatics (SACI), 2019;
DOI - https://doi.org/10.1109/SACI46893.2019.9111510

Cristian G. Zimbru, Nicoleta Andreescu, Adriana Albu, Adela Chirita-Emandi, Antonius Stanciu, Maria Puiu, „Performance Evaluation of In Silico Predictors for the Classification of Clinvar Variants”, 2019 E-Health and Bioengineering Conference (EHB), 2019;
DOI - https://doi.org/10.1109/EHB47216.2019.8969963

Vlad Serafim, Adela Chirita-Emandi, Nicoleta Andreescu, Diana-Andreea Tiugan, Paul Tutac, Corina Paul, Iulian Velea, Alexandra Mihailescu, Costela Lăcrimioara Șerban, Cristian G. Zimbru, Maria Puiu, Mihai Dinu Niculescu, „Single Nucleotide Polymorphisms in PEMT and MTHFR Genes are Associated with Omega 3 and 6 Fatty Acid Levels in the Red Blood Cells of Children with Obesity”, Nutrients (FI 4.17), vol. 11, no. 11, pp 2600, 2019;
DOI - https://dx.doi.org/10.3390%2Fnu11112600

Adriana Albu, Loredana Stanciu, Mădălina-Sofia Pașca, Cristian G. Zimbru, „Choosing Between Artificial Neural Networks and Bayesian Inference in Stroke Risk Prediction”, 2019 E-Health and Bioengineering Conference (EHB), 2019;
DOI - https://doi.org/10.1109/EHB47216.2019.8970035

Diana Miclea, Camelia Al-Khzouza, Sergiu Osan, Simona Bucerzan, Victoria Cret, Radu Anghel Popp, Maria Puiu, Adela Chirita-Emandi, Cristian Zimbru, Cristina Ghervan, „Genomic study via chromosomal microarray analysis in a group of Romanian patients with obesity and developmental disability/intellectual disability”, J Pediatr Endocrinol Metab 2019; 32(7): 667–674;
DOI - https://doi.org/10.1515/jpem-2018-0439

Vlad-Ilie Ungureanu, Bianca-Alexandra Trutiu, Ioan Silea, Paul Negirla, Cristian Zimbru, Razvan-Catalin Miclea, „Automatic mapping of a room using LIDAR-based measuring sensor”, 22nd International Conference on Control Systems and Computer Science (CSCS), pp. 689-695, 2019;
DOI - https://doi.org/10.1109/CSCS.2019.00123

2017

Cristian G. Zimbru, Nicoleta Andreescu, Adela Chirita-Emandi, Antonius Stanciu, Ioan Silea, Mihai D. Niculescu, Maria Puiu, Splice site pattern analysis and identification of similar sequences in the deep intron areas of human chromosome 21, 2017 E-Health and Bioengineering Conference (EHB), 2017;
DOI - https://doi.org/10.1109/EHB.2017.7995382

Cristian G. Zimbru, Nicoleta Andreescu, Adela Chirita-Emandi, Ioan Silea, Maria Puiu, Mihai D. Niculescu, Analysis of decision tree performance in predicting the relationship between a scored outcome and multiple single nucleotide polymorphisms, 2017 E-Health and Bioengineering Conference (EHB), 2017;
DOI - https://doi.org/10.1109/EHB.2017.7995360

Florina Stoica, Adela Chirita-Emandi, Nicoleta Andreescu, Alina Stanciu, Cristian G. Zimbru, Maria Puiu, Clinical relevance of retinal structure in children with laser-treated retinopathy of prematurity versus controls - using optical coherence tomography, Acta Ophthalmologica, 2017;
DOI - https://doi.org/10.1111/aos.13536

Posters & Abstracts

2016

Cristian Zimbru, Nicoleta Andreescu, Adela Chirita Emandi, Ioan Silea, Maria Puiu, Deep intron splice site-like sequences evidence for introns late theory, The IX Conference on Medical Genetics with International Participation, 22-24 September 2016, Poster session;

Maria Puiu, Nicoleta Andreescu, Simona Farcas, Cristian Zimbru, Adela Chirita-Emandi, Molecular genetics for the patients - prioritization criteria in the face of limited resources, European Society Human Genetics Confrence, Barcelona, 21-24 May 2016;

Cristian Zimbru, Nicoleta Andreescu, Adela Chirita-Emandi, Antonius Stanciu, Ioan Silea, Maria Puiu, Detection of high-risk intron areas that can cause splicing errors, Advanced Lecture Course on Systems Biology, Innsbruck, March 2016, Poster session;

Cristian Zimbru, Nicoleta Andreescu, Adela Chirita-Emandi, Maria Puiu, Specialistul bioinformatician în analiza genomului, ColaboRARE Conference, Bucharest, 29 – 30 January 2016;

Grants, Fellowships & Prizes

EHB 2017 - Third Prize Cristian ZIMBRU et al. for paper "Splice Site Pattern Analysis and Identification of Similar Sequences in the Deep Intron Areas of Human Chromosome 21"

Young Scientist Fellowship won for Advanced Lecture Course on Systems Biology, Innsbruck, 28 February – 5 March 2016